Allelyn enables hospitals and laboratories to perform genetic analysis in-house. Patient data is processed securely without leaving the laboratory, fully compliant with data protection regulations.
From Sequencer to Clinical Report
Speed, Accuracy and Security in Genetic Analysis — One Platform
Allelyn is an end-to-end genetic variant analysis platform running on NVIDIA DGX Spark. It takes raw data from your sequencer and produces a signed clinical report in 45 minutes. No bioinformatician needed.
15+
Reference Databases
8
Ready Pipelines
Medical GeneticsGermline AnalysisSomatic OncologyTrio AnalysisPharmacogenomicsCarrier ScreeningPrenatal AnalysisMitochondrial DNAExome AnalysisMedical GeneticsGermline AnalysisSomatic OncologyTrio AnalysisPharmacogenomicsCarrier ScreeningPrenatal AnalysisMitochondrial DNAExome AnalysisAbout Allelyn
From FASTQ to a signed clinical report — in 45 minutes
How Does It Work?
1B+
Total Variant Records
Total variant count compiled from ClinVar, gnomAD, COSMIC, dbSNP, OMIM and other databases.
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Analysis Types
For Hospitals and Labs of Every Scale
Each analysis type includes automated classification with 28 ACMG/AMP criteria, annotation with 15 reference databases, and clinical report generation.
Runs offline on your desktop.
Why Allelyn
GPU-powered analysis in seconds
GPU-accelerated annotation engine analyzes 50,000 variants in under 1 second. Integration with 15 databases including ClinVar, gnomAD, REVEL, AlphaMissense.
100% Local — Fully Compliant
All data stays on the device. No data is sent to the cloud, internet, or external servers.
FASTQ→Report in 45 Minutes
Panel analysis in 5 minutes, exome in 15 minutes, whole genome in 45 minutes.
Our Technology
End-to-end genetic analysis pipeline
From FASTQ file to signed clinical report — the entire process runs automatically on a single device.
99%
Analysis Accuracy
Classification accuracy compliant with ACMG/AMP criteria.
GPU-Accelerated Annotation
Matches 50,000 variants against 15 reference databases in under 1 second. Unmatched speed with JAX-based GPU engine.
ACMG/AMP Classification
Automated 5-tier classification with 28 evidence criteria. Pathogenic, Likely Pathogenic, VUS, Likely Benign, and Benign.
Automated Clinical Report
Ready-to-sign clinical reports generated in Turkish and English as PDF. Fully HGVS nomenclature compliant.
15 Reference Databases
ClinVar, gnomAD v4, COSMIC, OMIM, PharmGKB, SpliceAI, CADD, REVEL, AlphaMissense and more.
Who Uses Allelyn
For laboratories of every scale
Trusted Genetic Analysis
Fully compliant with ACMG/AMP standards, 100% local and data protection compliant platform.
How It Works
From FASTQ to report — step by step
Allelyn's analysis process is built on clarity, accuracy, and compliance with clinical standards. From the moment a FASTQ file is loaded, alignment, variant calling, annotation, ACMG classification, and report generation happen automatically.
Step 01
FASTQ Input
Transfer the FASTQ file from your sequencer to Allelyn. Via USB or local network.
Step 02
Automated Analysis Pipeline
Allelyn automatically performs alignment, variant calling, annotation, and ACMG classification.
Step 03
Clinical Report Generation
Advanced technology and strict quality controls ensure all analysis processes are executed with precision.
Our Solutions
Choose the right solution for your needs
Desktop or server — two solutions tailored to your laboratory needs.
Allelyn ONE
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Desktop solution running on NVIDIA DGX Spark. Ideal for small to mid-size laboratories.
- All analysis types
- 15 reference databases
- Clinical report
- Technical support included
Allelyn Server
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Enterprise solution running on NVIDIA DGX Server. For high-volume analysis needs.
- All analysis types
- 15 reference databases
- Clinical report
- Technical support included
Frequently Asked Questions
Browse our most asked questions
The most commonly asked questions about Allelyn.
Allelyn is an end-to-end genetic variant analysis platform running on NVIDIA DGX Spark or DGX Server. It takes FASTQ or VCF files from your sequencer and automatically performs alignment, variant calling, annotation, ACMG/AMP classification, and clinical report generation. The entire process is completed in your laboratory without needing a bioinformatician or cloud connection.
No, it is not mandatory. Allelyn supports both FASTQ and VCF formats. If you don't have your own NGS device, you can analyze VCF files obtained from external laboratories. If you have an NGS device, the entire pipeline runs automatically from the FASTQ file.
Illumina (MiSeq, NextSeq, NovaSeq), MGI (DNBSEQ-G400, DNBSEQ-T7), Ion Torrent, and all platforms producing standard FASTQ/VCF output are supported. No device-specific adapters are needed — standard FASTQ format is sufficient.
Allelyn supports 8 analysis types: Germline analysis, Somatic/Oncology analysis, Trio (family) analysis, Pharmacogenomics, Carrier screening, Prenatal analysis, Mitochondrial DNA analysis, and whole Exome analysis. Each analysis type includes automated classification with 28 ACMG/AMP criteria.
With the GPU-accelerated pipeline, a single patient panel analysis takes under 5 minutes, WES (whole exome) analysis approximately 15 minutes, and whole genome analysis 45 minutes. The annotation engine matches 50,000 variants against 15 reference databases in under 1 second.
